| Title |
A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications
|
|---|---|
| Published in |
Qeios, April 2020
|
| DOI | 10.32388/fxgqsb |
| Authors |
jean-pierre CHANGEUX, Zahir Amoura, Felix Rey, Makoto Miyara |
| Abstract |
SARS-CoV-2 epidemics raises a considerable issue of public health at the planetary scale. There is a pressing urgency to find treatments based upon currently available scientific knowledge. Therefore, we tentatively propose a hypothesis which hopefully might ultimately help saving lives. Based on the current scientific literature and on new epidemiological data which reveal that current smoking status appears to be a protective factor against the infection by SARS-CoV-2 [1], we hypothesize that the nicotinic acetylcholine receptor (nAChR) plays a key role in the pathophysiology of Covid-19 infection and might represent a target for the prevention and control of Covid-19 infection. |
X Demographics
The data shown below were collected from the profiles of 862 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 91 | 11% |
| United Kingdom | 45 | 5% |
| South Africa | 41 | 5% |
| Argentina | 26 | 3% |
| France | 23 | 3% |
| Spain | 18 | 2% |
| Germany | 17 | 2% |
| Canada | 17 | 2% |
| Turkey | 14 | 2% |
| Other | 143 | 17% |
| Unknown | 427 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 785 | 91% |
| Scientists | 44 | 5% |
| Practitioners (doctors, other healthcare professionals) | 19 | 2% |
| Science communicators (journalists, bloggers, editors) | 13 | 2% |
| Unknown | 1 | <1% |
Mendeley readers
The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 16 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 3 | 19% |
| Other | 2 | 13% |
| Student > Doctoral Student | 2 | 13% |
| Professor | 1 | 6% |
| Student > Ph. D. Student | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 6 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 3 | 19% |
| Social Sciences | 2 | 13% |
| Arts and Humanities | 1 | 6% |
| Nursing and Health Professions | 1 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 6% |
| Other | 2 | 13% |
| Unknown | 6 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2079. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2024.
All research outputs
#4,369
of 25,736,439 outputs
Outputs from Qeios
#2
of 1,380 outputs
Outputs of similar age
#316
of 404,839 outputs
Outputs of similar age from Qeios
#2
of 53 outputs
Altmetric has tracked 25,736,439 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,380 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 404,839 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.